« Back
Home /
H-Ile-Pro-Pro-OH (hydrochloride)

H-Ile-Pro-Pro-OH (hydrochloride)

Item no.	CS-0129355-250mg
Manufacturer	ChemScene
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1208862-61-6
Similar products	1208862-61-6
Available
CAS	1208862-61-6
Purity	>98%
MWt	361.86
Formula	C16H28ClN3O4
Solubility	H2O : 55 mg/mL (151.99 mM; Need ultrasonic); DMSO : 36.67 mg/mL (101.34 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Angiotensin-converting Enzyme (ACE)
Biological Activity	H-Ile-Pro-Pro-OH hydrochloride, a milk-derived peptide^[1], inhibits angiotensin-converting enzyme (ACE)^[1] with an IC₅₀ of 5 uM^[2]. Antihypertensive tripeptides^[1]. IC50 & Target: IC50: 5 uM (ACE)^[2] In Vitro: Ile-Pro-Pro (IPP; 1 nM, 0.1 uM, and 10 uM) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)^[1]. In Vivo: Ile-Pro-Pro (IPP; 30 mg/kg per day; 0.3 g/L) attenuates arterial dysfunction in L-NAME-treated rats^[1] Ile-Pro-Pro decreases blood pressure in spontaneously hypertensive rats (SHR) ^[1]. Ile-Pro-Pro attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice^[1].
Research Area	Cardiovascular Disease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 250mg

available

Delivery expected until 9/4/2025

Express Delivery: Save 7 days

Compare

Add to wishlist

Get an offer