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Apovincaminic acid (hydrochloride salt)

Apovincaminic acid (hydrochloride salt)

Item no.	CS-0133788-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Hematology Myeloma Sarcoma Reagents & Chemicals Molecules By Organ Lung Cancer
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	72296-47-0
Similar products	72296-47-0
Available
CAS	72296-47-0
Purity	>98%
MWt	358.86
Formula	C20H23ClN2O2
Solubility	10 mM in DMSO
Clinical Information	No Development Reported
Pathway	Metabolic Enzyme/Protease
Target	Drug Metabolite
Biological Activity	Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action^[1]^[2]. In Vivo: Apovincaminic acid (10 mg/kg; i.p. twice daily for 4 days) effectively attenuates the behavioral deficits, and significantly decreases lesion size and the region of microglia activation^[1]. Apovincaminic acid (10 mg/kg; p.o.) is absorbed 50% of the dose comparing with i.v. administration in rats^[2].
Research Area	Neurological Disease

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Amount: 5mg

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