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Fostemsavir Tris

Fostemsavir Tris

Item no.	CS-1060-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	864953-39-9
Similar products	864953-39-9
Available
Alternative Names	BMS-663068 (Tris)
CAS	864953-39-9
Purity	>98%
MWt	704.62
Formula	C29H37N8O11P
Solubility	H2O : 100 mg/mL (141.92 mM; Need ultrasonic); DMSO : 125 mg/mL (177.40 mM; Need ultrasonic)
Clinical Information	Phase 3
Pathway	Anti-infection
Target	HIV
Biological Activity	Fostemsavir Tris (BMS-663068 (Tris)) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir Tris (BMS-663068 (Tris)) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4⁺ T cells. IC50 & Target: HIV-1^[1] In Vivo: Fostemsavir Tris has good antiviral activity in subjects infected with virus shown to be susceptible (IC₅₀, <100 nM) to the agent^[1].
Research Area	Infection

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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