Carvedilol

72956-09-3

C24H26N2O4

DMSO : >= 205 mg/mL (504.34 mM)

GPCR/G Protein; Autophagy; Neuronal Signaling

Carvedilol(BM14190) is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 uM for inhibition of LDL oxidation. IC50 Value: 3.8 uM ( inhibition of LDL oxidation) Target: beta Adrenergic Receptor Carvedilol is a nonselective-blocking agent and is used in the treatment of hypertension and angina pectoris. As a third-generation beta-adrenergic blocker (beta-blocker), Carvedilol is able to reverse cardiac structural remodeling. Recentresults demonstrated that the effect caused by Carvedilol on cardiac remodeling is largely dependent on endogenous NO.