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Poloxime

Poloxime

Item no.	CS-1334-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	17302-61-3
Available
CAS	17302-61-3
Purity	>98%
Formula	C10H13NO2
MWt	179.22
Solubility	H2O : < 0.1 mg/mL (insoluble); DMSO : >= 100 mg/mL (557.97 mM)
Clinical Information	No Development Reported
Pathway	Cell Cycle/DNA Damage
Target	Polo-like Kinase (PLK)
Biological Activity	Poloxime, a hydrolysis product of poloxin, is a non-ATP-competitive Plk1 inhibitor, with moderate Plk1 inhibitory activity. IC50 & Target: PLK1^[1] In Vitro: Poloxime (100 uM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1)^[2].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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