Comparison

Trilostane

Item no. CS-1707-100mg
Manufacturer ChemScene
Amount 100mg
Category
Type Molecules
Specific against other
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Similar products 13647-35-3
Available
Alternative Names
Win 24540
CAS
13647-35-3
Purity
>98%
Formula
C20H27NO3
MWt
329.43
Solubility
DMSO : >= 56 mg/mL (169.99 mM); H2O : < 0.1 mg/mL (insoluble)
Clinical Information
Launched
Pathway
Others
Target
Others
Biological Activity
Trilostane(Win 24540; Modrastane) is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. IC50 value: Target: 3 beta-HSD Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase (3-beta-HSD or delta 5-delta 4-isomerase), an essential enzyme for the biosynthesis of all classes of hormonal steroids. It has been used in the treatment of Cushing?s syndrome for stopping the production of cortisol, and is currently approved for dogs in the US, but is still a human drug in the UK and other countries. It is being investigated as a possible treatment for both breast cancer and prostate cancer to prevent the synthesis of estrogens and androgens from endogenous precursors. It has also been used to inhibit endogenous production of progesterone in research studies.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100mg
Available: In stock
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