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Bumetanide

Bumetanide

Item no.	CS-1821-1g
Manufacturer	ChemScene
CASRN	28395-03-1
Amount	1g
Category	Cardiovascular Research Heart Failure Hypertension Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	28395-03-1
Available
Alternative Names	Ro 10-6338; PF 1593
CAS	28395-03-1
Purity	>98%
Formula	C17H20N2O5S
MWt	364.42
Solubility	DMSO : >= 100 mg/mL (274.41 mM); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	Launched
Pathway	Membrane Transporter/Ion Channel
Target	NKCC
Biological Activity	Bumetanide (Ro 10-6338; PF 1593) is a selective Na⁺-K⁺-Cl^- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC₅₀s of 0.68 and 4.0 uM for hNKCC1A and hNKCC2A, respectively^[4].

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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