Salbutamol (hemisulfate)

51022-70-9

C13H22NO5S0.5

H2O : >= 130 mg/mL (451.17 mM)

GPCR/G Protein; Autophagy; Autophagy; Neuronal Signaling

Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting beta2 adrenergic receptor agonist Target: beta2 Adrenergic Receptor Salbutamol Hemisulfate (Albuterol hemisulfate) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. All the effects of R, S-salbutamol on guinea-pig skeletal muscles are due to the activity of the R-enantiomer. Thus there is a common enantiomeric profile for the skeletal muscle and bronchorelaxant activity of the compound [1]. Short-term Salbutamol intake did appear to improve performance during intense submaximal exercise with concomitant increase in substrate availability and utilization, but the exact mechanisms involved need further investigation [2]. Short-term administration of salbutamol increases voluntary muscle strength in man. However, the magnitude and duration of this effect vary between muscle groups. This study implies that the beta 2-adrenoceptor agonists may be of therapeutic potential in altering skeletal muscle function in humans [3].