GSK-J2

Item no.	CS-3260-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1394854-52-4
Similar products	1394854-52-4
Available
CAS	1394854-52-4
Purity	>98%
MWt	389.45
Formula	C22H23N5O2
Solubility	DMSO : >= 42 mg/mL (107.84 mM)
Clinical Information	No Development Reported
Pathway	Epigenetics
Target	Histone Demethylase
Biological Activity	GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A. In Vitro: GSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC₅₀ of > 100 uM and 49 uM, respectively^[1].
Research Area	Cancer

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