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Tolazoline (hydrochloride)

Tolazoline (hydrochloride)

Item no.	CS-4287-100g
Manufacturer	ChemScene
Amount	100g
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	59-97-2
Similar products	59-97-2
Available
Alternative Names	Imidaline (hydrochloride); NSC35110 (hydrochloride)
CAS	59-97-2
Purity	>98%
MWt	196.68
Formula	C10H13ClN2
Solubility	DMSO : 33.33 mg/mL (169.46 mM; Need ultrasonic); H2O : >= 50 mg/mL (254.22 mM)
Clinical Information	Launched
Pathway	GPCR/G Protein; Neuronal Signaling
Target	Adrenergic Receptor; Adrenergic Receptor
Biological Activity	Tolazoline (hydrochloride)(Imidaline (hydrochloride)) Hcl is a non-selective competitive alpha-adrenergic receptor antagonist. IC50 value: Target: alpha-adrenoceptor antagonist Tolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of tolazoline is strikingly similar to alpha-adrenergic agonists, which are antiedema sympathomimetics.
Research Area	Endocrinology

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