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ERK5-IN-1

ERK5-IN-1

Item no.	CS-4938-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Neuroscience Molecular Targets for Neuroscience Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1234479-76-5
Available
CAS	1234479-76-5
Purity	>98%
Formula	C25H29N7O2
MWt	459.54
Solubility	DMSO : >= 100 mg/mL (217.61 mM)
Clinical Information	No Development Reported
Pathway	Stem Cell/Wnt; MAPK/ERK Pathway
Target	ERK; ERK
Biological Activity	ERK5-IN-1 is a potent ERK5 inhibitor with an IC₅₀ of 87+/-7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC₅₀ of 26 nM. IC50 & Target: IC50: 87+/-7 nM (ERK5), 26 nM (LRRK2[G2019S])^[1] In Vitro: ERK5-IN-1 (Compound 5) exhibits a cellular EC₅₀ for inhibiting epidermal growth factor (EGF) induced ERK5 autophosphorylation of 0.19+/-0.04 uM^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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