ISX-9

Item no.	CS-5072-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	832115-62-5
Available
Alternative Names	Isoxazole 9
CAS	832115-62-5
Purity	>98%
Formula	C11H10N2O2S
MWt	234.27
Solubility	DMSO : >= 37 mg/mL (157.94 mM)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 uM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.

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