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Neuromedin N

Neuromedin N

Item no.	CS-5506-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Metabolism Diabetes Glucose Homeostasis Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	92169-45-4
Available
Alternative Names	Neuromedin N (rat, mouse, porcine, canine)
CAS	92169-45-4
Purity	>98%
Formula	C38H63N7O8
MWt	745.95
Solubility	H2O : 50 mg/mL (67.03 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	GPCR/G Protein; Neuronal Signaling
Target	Dopamine Receptor; Dopamine Receptor
Biological Activity	Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. IC50 & Target: Dopamine D2 receptor^[1]. In Vitro: Neuromedin N competitively inhibits the binding of neurotensin to rat brain synaptic membranes with a 19-fold lower potency than neurotensin and is rapidly inactivated by brain synaptic peptidases^[1]. It competitively inhibits neurotensin binding to rat brain synaptic membranes and has increased potency in the presence of the peptidase inhibitor bestatin^[2].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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