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Fumarate hydratase-IN-2 (sodium salt)

Fumarate hydratase-IN-2 (sodium salt)

Item no.	CS-5727-25mg
Manufacturer	ChemScene
Amount	25mg
Category	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Carcinoma Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Purity	>98%
Formula	C25H25N2NaO4
MWt	440.47
Solubility	DMSO : 10.66 mg/mL (24.20 mM; Need ultrasonic and warming)
Clinical Information	No Development Reported
Pathway	Others
Target	Others
Biological Activity	Fumarate hydratase-IN-2 sodium salt is an enzyme of the TCA cycle and cell-permeable inhibitor. (1) inhibition of fumarate hydratase can contribute to tumorigenicity in some cells. (2) The use of a photoaffinity labeling strategy identified fumarate hydratase as the principal pharmacological target. Final biochemical studies confirmed dose-dependent, competitive inhibition of this enzyme (3) Chemical inhibition of fumarate hydratase renders cells highly dependent on glucose metabolism for survival.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 10/2/2025

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