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R1487 (Hydrochloride)

R1487 (Hydrochloride)

Item no.	CS-5860-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	449808-64-4
Available
CAS	449808-64-4
Purity	>98%
Formula	C19H19ClF2N4O3
MWt	424.83
Solubility	DMSO : 20.83 mg/mL (49.03 mM; Need ultrasonic); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	No Development Reported
Pathway	MAPK/ERK Pathway
Target	p38 MAPK
Biological Activity	R1487 (Hydrochloride) is highly potent and highly selective inhibitors of p38alpha. target: p38alpha; R1487 (Hydrochloride) potently inhibits cytokine production in a variety of in vitro and in vivo models.[1] R1487 (Hydrochloride) inhibits production of TNFR by human monocytic cells (THP-1) and inhibits production of IL-1beta in human whole blood (HWB) induced by LPS.[1]

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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