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Mavoglurant (racemate)

Mavoglurant (racemate)

Item no.	CS-6126-2mg
Manufacturer	ChemScene
Amount	2mg
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	1636881-61-2
Available
Alternative Names	AFQ-056 racemate
CAS	1636881-61-2
Purity	>98%
Formula	C19H23NO3
MWt	313.39
Solubility	DMSO : 50 mg/mL (159.55 mM; Need ultrasonic)
Clinical Information	No Development Reported
Pathway	GPCR/G Protein; Neuronal Signaling
Target	mGluR; mGluR
Biological Activity	Mavoglurant (racemate) is the racemate of mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. In Vitro: For antagonistic activity, (?)-mavoglurant, the (?)-enantiomer shows IC₅₀ of 0.11 uM and 0.03 uM (Ca²⁺ and PI-turnover) whereas the (+)-enantiomer ((+)-10) shows only 37% and 18% inhibition at 10 uM^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 2mg

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