« Back
Home /
Dutogliptin

Dutogliptin

Item no.	CS-6633-10mg
Manufacturer	ChemScene
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	852329-66-9
Similar products	852329-66-9
Available
Alternative Names	PHX-1149 (free base)
CAS	852329-66-9
Purity	>98%
MWt	241.10
Formula	C10H20BN3O3
Solubility	DMSO : 300 mg/mL (1244.30 mM; Need ultrasonic)
Clinical Information	Phase 3
Pathway	Metabolic Enzyme/Protease
Target	Dipeptidyl Peptidase
Biological Activity	Dutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. IC50 & Target: DPP4^[1] In Vivo: Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a T_max of 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s^[2].
Research Area	Metabolic Disease

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10mg

available

Delivery expected until 7/3/2025

Express Delivery: Save 21 days

Compare

Add to wishlist

Recommend by mail