Neurotensin(8-13)

60482-95-3

C38H64N12O8

H2O : 50 mg/mL (61.20 mM; Need ultrasonic)

Others

Neurotensin (8-13) is an active fragment of Neurotensin, . Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. Sequence: Arg-Arg-Pro-Tyr-Ile-Leu. IC50 & Target: NTR1^[1] In Vitro: Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different^[1].