EP1013

Item no.	CS-7645-5mg
Manufacturer	ChemScene
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	223568-55-6
Available
Alternative Names	F1013
CAS	223568-55-6
Purity	>98%
Formula	C18H23FN2O6
MWt	382.38
Solubility	DMSO : >= 60 mg/mL (156.91 mM)
Clinical Information	No Development Reported
Pathway	Apoptosis
Target	Caspase
Biological Activity	EP1013 is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes. In Vivo: EP1013 (1, 3, 10 mg/kg) significantly improves marginal islet mass function. Two animals in the 10 mg/kg EP1013 treatment group exhibit primary islet graft nonfunction, but the diabetes reversal rate for this group is not significantly different from the 3 mg/kg EP1013, 1 mg/kg EP1013, or 10 mg/kg zVAD groups. EP1013 therapy enhances functional syngeneic islet mass and promotes longevity of islet graft function^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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