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p38-alpha MAPK-IN-1

p38-alpha MAPK-IN-1

Item no.	CS-7765-100mg
Manufacturer	ChemScene
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Similar products	443913-15-3
Available
CAS	443913-15-3
Purity	>98%
Formula	C27H35N5O3
MWt	477.60
Solubility	DMSO : >= 100 mg/mL (209.38 mM); H2O : < 0.1 mg/mL (insoluble)
Clinical Information	No Development Reported
Pathway	MAPK/ERK Pathway
Target	p38 MAPK
Biological Activity	p38-alpha MAPK-IN-1 is an inhibitor of MAPK14 (p38-alpha), with IC₅₀ of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. IC50 & Target: IC50: 2300 nM (p38-alpha, in EFC assay), 5500 nM (p38-alpha, in HTRF assay)^[1] In Vitro: p38-alpha MAPK-IN-1 (Compound 12) is an inhibitor of MAPK14 (p38-alpha)>, with IC₅₀ of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay^[1].

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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