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Thalidomide 4-fluoride

Thalidomide 4-fluoride

Item no.	CS-B1597-50mg
Manufacturer	ChemScene
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	835616-60-9
Similar products	835616-60-9
Available
Alternative Names	Cereblon ligand 4; E3 ligase Ligand 4
CAS	835616-60-9
Purity	>98%
MWt	276.22
Formula	C13H9FN2O4
Solubility	DMSO : 200 mg/mL (724.06 mM; Need ultrasonic and warming)
Clinical Information	No Development Reported
Pathway	PROTAC
Target	Ligand for E3 Ligase
Biological Activity	Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966)^[1].
Research Area	Cancer

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Amount: 50mg

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