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Danicopan (ACH-4471)

Danicopan (ACH-4471)

Item no.	DCC-DC11082-250mg
Manufacturer	DCChemicals
CASRN	1903768-17-1
Amount	250 mg
Quantity options	100 mg 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	IC, Blocking, other
Specific against	other
Purity	>98%
Smiles	N(C(CN1C2=C(C=C(C3=CN=C(C)N=C3)C=C2)C(C(C)=O)=N1)=O)1C[C@@H](F)C[C@@H]1C(NC1=NC(Br)=CC=C1)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ACH-4471,ACH4471,ACH-0144471
Similar products	1903768-17-1
Available
Manufacturer - Applications	Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
Molecular Weight	580, 418
Chemical name	(2S, 4R)-1-{[3-acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine2-carboxamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 3/5/2026

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