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OTS186935

OTS186935

Item no.	DCC-DC11257-10mg
Manufacturer	DCChemicals
CASRN	2093400-18-9
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg
Category	In Vivo Reagents & Chemicals Molecules
Type	Inhibitors
Applications	IV
Specific against	other
Purity	>98%
Smiles	N(C1C=CN2C=C(C3=CC(Cl)=C(OC)C=C3OC)N=C2C=1)1CC[C@@H](NCC2C=CN=CC=2)C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	OTS-186935;OTS 186935
Similar products	2093400-18-9
Available
Manufacturer - Applications	OTS186935 (OTS-186935) is a potent, in vivo-active inhibitor of protein methyltransferase SUV39H2 with IC50 of 6.49 nM, inhibits A549 cell growth with IC50 of 0.67 uM; causes a significant growth inhibitory effect in mouse xenograft models using MDA-MB-231 breast cancer cells as well as A549 lung cancer cells, at 25 mg/kg once daily for 14 days yielded a TGI of 60.8%; attenuates the levels of H3K9me3 in A549 xenograft mouse model.
Storage Conditions	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Molecular Weight	463, 966
Note	For research and scientific purpose only, not for human use.
Chemical name	(S)-1-(2-(5-chloro-2, 4-dimethoxyphenyl)imidazo[1, 2-a]pyridin-7-yl)-N-(pyridin-4-ylmethyl)pyrrolidin-3-amine

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 12/11/2025

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