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PF-5274857

PF-5274857

Item no.	DCC-DC12373-100mg
Manufacturer	DCChemicals
CASRN	1373615-35-0
Amount	100 mg
Quantity options	100 mg 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	IC
Specific against	other
Purity	>98%
Smiles	O=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	PF-5274857,PF 5274857,PF5274857
Similar products	1373615-35-0
Available
Manufacturer - Applications	PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the blood–brain barrier.
Storage Conditions	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Molecular Weight	436, 96
Note	For research and scientific purpose only, not for human use.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 3/5/2026

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