AKI603

Item no.	DCC-DC20650-5mg
Manufacturer	DCChemicals
CASRN	1432515-73-5
Amount	5 mg
Quantity options	100 mg 1 g 250 mg 5 mg
Category	Reagents & Chemicals Molecules Immunochemistry
Type	Inhibitors
Applications	IC, other
Specific against	other
Purity	>98%
Smiles	CC1=CC(=NN1)NC2=CC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCN(CC4)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1432515-73-5
Similar products	1432515-73-5
Available
Manufacturer - Applications	AKI-603 is a novel small molecule Aurora A kinase inhibitor with IC50 of 12.3 nM, also inhibits Aurora B kinase activity to a less extent; disrupts normal spindle structure, and induces cell-cycle arrest; t; suppresses stem cell properties in breast cancer cells, and also suppresses the expression of self-renewal genes (β-catenin, c-Myc, Sox2, and Oct4); reduces xenograft tumor growth after intragastric administration.
Molecular Weight	409, 454

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 1/1/2026

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