« Back
Home /
AZD 4205

AZD 4205

Item no.	DCC-DC20726-250mg
Manufacturer	DCChemicals
CASRN	2091134-68-6
Amount	250 mg
Quantity options	100 mg 1 g 250 mg
Category	Reagents & Chemicals Molecules
Type	Inhibitors
Applications	IV
Specific against	other
Smiles	O=C([C@@H](C)N1CCN(C)[C@H](C)C1)NC2=CC=CC3=C2NC=C3C4=C(F)C=NC(NC5=CN(C)N=C5OC)=N4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AZD4205,AZD-4205
Similar products	2091134-68-6
Available
Manufacturer - Applications	AZD 4205 (AZD4205) is a potent, selective JAK1 inhibitor IC50 of 73 nM and Ki of 2.8 nM, shows high selectivity against JAK2 and JAK3 with IC50 of 13, 233 nM and >30, 000 nM respectively; shows potent inhibition of p-STAT3 in a cell based assay of JAK1 activity with an IC50 of 128 nM and excellent selectivity across the kinome; reduces residual disease and prolongs the benefit of Osimertinib in lung cancer patients with EGFR activating mutations both in vitro and in vivo.
Storage Conditions	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Molecular Weight	521, 601
Note	For research and scientific purpose only, not for human use.
Chemical name	(R)-N-(3-(2-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-2-(4-methylpiperazin-1-yl)propanamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 250 mg

available

Delivery expected until 9/11/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer