MS4078

Item no.	DCC-DC21351-10mg
Manufacturer	DCChemicals
CASRN	2229036-62-6
Amount	10 mg
Quantity options	100 mg 10 mg 25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	MS
Specific against	other
Purity	>98%
Smiles	CC(C)S(C1=C(NC2=NC(NC3=C(OC(C)C)C=C(C4CCN(CC(NCCNC5=C(C(N(C6C(NC(CC6)=O)=O)C7=O)=O)C7=CC=C5)=O)CC4)C(C)=C3)=NC=C2Cl)C=CC=C1)(=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MS-4078;MS 4078
Similar products	2229036-62-6
Available
Manufacturer - Applications	MS4078 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=11 nM).
Storage Conditions	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Molecular Weight	914, 47
Note	For research and scientific purpose only, not for human use.
Chemical name	2-(4-(4-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-5-isopropoxy-2-methylphenyl)piperidin-1-yl)-N-(2-((2-(2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindolin-4-yl)amino)ethyl)acetamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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Delivery expected until 3/5/2026

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