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LY487379

LY487379

Item no.	DCC-DC22435-250mg
Manufacturer	DCChemicals
CASRN	353231-17-1
Amount	250 mg
Quantity options	100 mg 1 g 250 mg
Category	Reagents & Chemicals Molecules
Type	Chemicals
Specific against	Rat (Rattus norvegicus)
Purity	>98%
Smiles	FC(F)(F)CS(N(C1C=CC(OC2C=CC=CC=2OC)=CC=1)CC1=CC=CN=C1)(=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	353231-17-1
Similar products	353231-17-1
Available
Manufacturer - Applications	LY-487379 is a potent, selective positive allosteric modulator of mGluR2 (EC50=0.27 uM) without activity at mGluR3; shows no intrinsic agonist or antagonist activity at hmGluR2, markedly potentiates glutamate-stimulated [35S]GTPgammaS binding at hmGluR2; potentiates synaptically evoked mGluR2 responses in rat hippocampal slices, modulates excitatory synaptic transmission in the rat globus pallidus.
Molecular Weight	452, 446

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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Delivery expected until 1/1/2026

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