Comparison

Pyr10

Item no. DCC-DC23945-250mg
Manufacturer DCChemicals
CASRN 1315323-00-2
Amount 250 mg
Quantity options 100 mg 10 mg 1 g 250 mg 50 mg
Category
Type Inhibitors
Applications IC
Specific against other
Purity >98%
Smiles O=S(=O)(NC1C=CC(N2C(C(F)(F)F)=CC(C(F)(F)F)=N2)=CC=1)C1C=CC(C)=CC=1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1315323-00-2
Similar products 1315323-00-2
Available
Manufacturer - Applications

Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels[1].
Molecular Weight
449, 3701

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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