Comparison

CC-90011 besylate

Item no. DCC-DC26140-250mg
Manufacturer DCChemicals
CASRN 2097523-60-7
Amount 250 mg
Quantity options 100 mg 1 g 250 mg
Category
Type Inhibitors
Applications Cell Culture
Specific against other
Purity >98%
Smiles N#CC1=CC=C(C(N=C(N2CCC(N)CC2)N3)=C(C4=CC=C(OC)C(F)=C4)C3=O)C=C1F.O=S(C5=CC=CC=C5)(O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias CC-90011,CC90011,CC 90011,CC-90011 besylate,
Similar products 2097523-60-7
Available
Manufacturer - Applications
CC-90011 is a potent and orally active LSD1 inhibitor. CC-90011 binds to and inhibits LSD1, a demethylase that suppresses the expression of target genes by converting the di- and mono-methylated forms of lysine at position 4 of histone H3 (H3K4) to mono- and unmethylated H3K4, respectively. CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell lines, and antitumor efficacy in patient-derived xenograft (PDX) SCLC models.
Molecular Weight
609, 6488
Chemical name
4-[2-(4-Amino-piperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-6-oxo-1, 6-dihydro-pyrimidin-4-yl]-2-fluoro-benzonitrile benzenesulfonic acid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 250 mg
Available: In stock
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