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GW-506033X(PKR Inhibitor C16)

GW-506033X(PKR Inhibitor C16)

Item no.	DCC-DC33146-100mg
Manufacturer	DCChemicals
CASRN	608512-97-6
Amount	100 mg
Quantity options	100 mg 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	IC
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Purity	>98%
Smiles	O=C1/C(C2=C(SC=N3)C3=CC=C2N1)=C\C4=CN=CN4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	608512-97-6
Similar products	608512-97-6
Available
Manufacturer - Applications	C16, also known as GW-506033X or PKR Inhibitor. C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. GW-506033X protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress. PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component. PKR inhibitor C16 binds efficiently with human microtubule affinity-regulating kinase 4.
Molecular Weight	268, 294

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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Delivery expected until 3/5/2026

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