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Foretinib(XL880)

Foretinib(XL880)

Item no.	DCC-DC7342-1g
Manufacturer	DCChemicals
CASRN	849217-64-7
Amount	1 g
Quantity options	100 mg 10 mM x 1 ml in DMSO 1 g 250 mg
Category	Reagents & Chemicals Molecules
Type	Chemicals
Specific against	other
Purity	>98%
Smiles	O=C(NC1=CC=C(C(F)=C1)OC2=C3C=C(C(OCCCN4CCOCC4)=CC3=NC=C2)OC)C5(CC5)C(NC6=CC=C(C=C6)F)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	XL-880,EXEL-2880,XL 880
Similar products	849217-64-7
Available
Manufacturer - Applications	Foretinib (GSK1363089; XL880; EXEL-2880; GSK089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR.
Molecular Weight	632, 65
Chemical name	N-(3-fluoro-4-(6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1, 1-dicarboxamide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 g

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Delivery expected until 11/13/2025

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