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Camptothecin

Camptothecin

Manufacturer	Leinco Technologies
Category	Reagents & Chemicals Other Chemicals APIs
Type	Small Molecules
Specific against	other
Amount	25mg
Item no.	LEIN-C2840-25mg
eClass 6.1	32160401
eClass 9.0	32160401
Available
Product Description	Camptothecin is a potent cytotoxic pentacyclic alkaloid known for its potent apoptosis inducing properties. Camptothecin and its analogs have been demonstrated to inhibit topoisomerase I (topo I), causing cells in S phase to enter into apoptosis. Camptothecin binds to and stabilizes the topo I – DNA backbone complex (covalent binary complex). This stabilized complex diminishes the rate of topo I release from the broken strand, thus slowing the religation and subsequent DNA synthesis process. Use camptothecin to create positive controls in apoptosis detection experiments.
Shipping Conditions	20°C
Storage and Stability	Storage: -20°C

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Amount: 25mg

available

Delivery expected until 5/23/2024