Anti-COVID-19 Traditional Chinese Medicine Compound Library

During the treatment of Covid-19 in China, the intervention of traditional Chinese medicine (TCM) reduced the severe symptoms of patients and played significant role in the war against COVID-19. Multiple research studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. TCM could suppress endotoxin-induced cytotoxicity, kill the virus, reduce the virus' access to the cell and lower the incidence of a cytokine storm. To further support the research in modes of action of TCM in the treatment of COVID-19, we extracted 1162 bioactive components (monomers) from TCM prescriptions having therapeutic effect.According to 17 TCM prescriptions used in the therapeutics of COVID-19, TargetMol extracted xnum natural product monomers with diverse structures such as flavonoids, alkaloids, polyphenols, Terpenes, etc. from 70 medicinal herbs, including Lonicera japonica Thunb., Forsythia suspensa, Scutellaria baicalensis Georgi, Bupleuri Radix, Agastache rugosa, Isatidis Radix, Rhodiola rosea, etc. to form the L6720.