Comparison

Sorafenib European Partner

Item no. TMO-T0093L-500mg
Manufacturer TargetMol
CASRN 284461-73-0
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 20 mg 2 mg 500 mg 50 mg
Category
Type Molecules
Format Powder
Specific against other
Purity 0,99
Smiles O(C=1C=C(C(NC)=O)N=CC1)C2=CC=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias Bay 43-9006
Shipping Condition Cool pack
Available
Manufacturer - Targets
VEGFR|||Ferroptosis|||Apoptosis|||FLT|||PDGFR|||Raf|||c-Kit|||Autophagy
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
464.82
Description
Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.
Pathways
Tyrosine Kinase/Adaptors|||MAPK|||Apoptosis|||Angiogenesis|||Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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