« Back
Home /
BACE1-IN-5

BACE1-IN-5

Item no.	TMO-T10453-500mg
Manufacturer	TargetMol
CASRN	2581114-83-0
Amount	500 mg
Quantity options	100 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	C[C@]1(C[C@@H](C(F)(F)F)SC(N)=N1)C2=CC(NC(=O)C=3C=NC(OCF)=CN3)=CC=C2F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	T10453
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Beta Amyloid\|\|\|BACE
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	461.41
Description	BACE1-IN-5 (Compound 15), a potent β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, demonstrates significant efficacy with an IC50 of 9.1 nM for BACE1 inhibition and an impressive IC50 of 0.82 nM against cellular amyloid-β (Aβ) production. Additionally, it is engineered to enhance hERG inhibition and P-gp efflux, indicating its optimized medicinal chemistry profile [1].
Pathways	Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T10453-500mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 500 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question