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Numidargistat dihydrochloride

Numidargistat dihydrochloride

Item no.	TMO-T10692-25mg
Manufacturer	TargetMol
Amount	25 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg 100 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,98
Smiles	O=C([C@@H](N)C)N1C[C@H](CCCB(O)O)[C@](N)(C(O)=O)C1.Cl.Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CB-1158 dihydrochloride,INCB01158 dihydrochloride,CB-1158 dihydrochloride ( free base),INCB 01158 dihydrochloride,CB1158 dihydrochloride
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Arginase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	360.04
Description	Numidargistat dihydrochloride (CB-1158 dihydrochloride) is an orally active and highly effective arginase (ARG1) inhibitor, an immuno-oncology agent that inhibits TGF-β2-induced subcapsular cataract by reducing the proliferation of lens epithelial cells (LEC) and decreasing the expression of fibronectin, α-SMA, collagen 1A1, and vimentin.
Pathways	Immunology/Inflammation

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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