Comparison

N-Desethyl Sunitinib European Partner

Item no. TMO-T12145-50mg
Manufacturer TargetMol
CASRN 356068-97-8
Amount 50 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Molecules
Format Powder
Specific against other
Purity 0,98
Smiles C(=C\1/C=2C(NC1=O)=CC=C(F)C2)\C3=C(C)C(C(NCCNCC)=O)=C(C)N3
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias SU11662,SU-11662
Shipping Condition Cool pack
Available
Manufacturer - Targets
PDGFR|||Drug Metabolite|||c-Kit|||VEGFR|||FLT
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
370.42
Description
N-Desethyl Sunitinib (SU012662) is the primary active metabolite of Sunitinib produced by the metabolism of cytochrome P450 enzyme 3A4 (CYP3A4).Sunitinib is an orally available inhibitor of a number of tyrosine kinases involved in tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3, and was approved for the treatment of advanced/metastatic renal cell carcinoma (RCC)
Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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