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Pelitrexol

Pelitrexol

Item no.	TMO-T14147-500mg
Manufacturer	TargetMol
CASRN	446022-33-9
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	O=C1C2=C(NC[C@@H](CCC=3SC(C(N[C@@H](CCC(O)=O)C(O)=O)=O)=CC3C)C2)NC(N)=N1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	AG 2037,AG2037
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Antifolate\|\|\|DHFR\|\|\|mTOR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	463.51
Description	Pelitrexol (AG2037) is a GARFT inhibitor, which can inhibit the activity of mTORC1, reduce intracellular guanine nucleotides and block the cell cycle in the s-phase, with antiproliferative activity, and can be used in non-small cell lung cancer.
Pathways	Cell Cycle/Checkpoint\|\|\|PI3K/Akt/mTOR signaling\|\|\|DNA Damage/DNA Repair\|\|\|Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T14147-500mg-datasheet.pdf

TMO-T14147-500mg-safety-datasheet.pdf