Comparison

MMV390048 European Partner

Item no. TMO-T16125-500mg
Manufacturer TargetMol
CASRN 1314883-11-8
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Smiles CS(=O)(=O)c1ccc(cc1)-c1cnc(N)c(c1)-c1ccc(nc1)C(F)(F)F
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias 1314883-11-8
Shipping Condition Cool pack
Available
Manufacturer - Targets
Parasite|||PI4K
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
393.38
Description
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns.
Pathways
Microbiology/Virology|||PI3K/Akt/mTOR signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
available

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