NVP-2

Item no.	TMO-T16363-1mg
Manufacturer	TargetMol
CASRN	1263373-43-8
Amount	1 mg
Quantity options	100 mg 100 mg 1 mL x 10 mM (in DMSO) 1 mL x 10 mM (in DMSO) 10 mg 10 mg 1 mg 1 mg 200 mg 25 mg 25 mg 2 mg 2 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	COC[C@@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1263373-43-8
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	513, 07
Description	NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases (IC50: 0.584 μM, 0.706 μM, and 0.605 μM, respectively).
Pathways	Cell Cycle/Checkpoint\|\|\|Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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