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7-Hydroxymethotrexate

7-Hydroxymethotrexate

Item no.	TMO-T20339-1mg
Manufacturer	TargetMol
CASRN	5939-37-7
Amount	1 mg
Quantity options	10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	Silva MF, Ribeiro C, Gonçalves VMF, Tiritan ME, Lima A. Liquid chromatographic methods for the therapeutic drug monitoring of methotrexate as clinical decision support for personalized medicine: A brief review. Biomed Chromatogr. 2018 May;32(5):e4159. doi: 10.1002/bmc.4159. Epub 2018 Jan 12. Review. PubMed PMID: 29226354.
Smiles	NC1=C2C(NC(=O)C(CN(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NSC380962,NSC380963,NSC-380963,NSC 380963,NSC 380962,NSC-380962
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Drug Metabolite
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	470.44
Description	7-Hydroxymethotrexate is the major metabolite of Methotrexate.Methotrexate is an inhibitor of folic acid, inhibiting dihydrofolate reductase, which prevents the conversion of folic acid to tetrahydrofolate, and inhibiting DNA synthesis.Methotrexate is also an inhibitor of metabolism.
Pathways	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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TMO-T20339-1mg-datasheet.pdf

TMO-T20339-1mg-safety-datasheet.pdf