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Losartan Carboxylic Acid

Losartan Carboxylic Acid

Item no.	TMO-T3461-2mg
Manufacturer	TargetMol
CASRN	124750-92-1
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,9928
Smiles	C(N1C(CCCC)=NC(Cl)=C1C(O)=O)C2=CC=C(C=C2)C3=C(C=CC=C3)C=4NN=NN4
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	EXP-3174,E-3174
Shipping Condition	Cool pack
Available
Manufacturer - Targets	RAAS
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	436.89
Description	Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), produces a depressor response and vasodilatation. As a metabolite of losartan, it is more potent than losartan in blocking angiotensin II-induced responses in vascular smooth muscle cells.
Pathways	Endocrinology/Hormones

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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