RSL3

Item no.	TMO-T3646-2mg
Manufacturer	TargetMol
CASRN	1219810-16-8
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 1 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,9996
Smiles	COC(=O)[C@H]1Cc2c([nH]c3ccccc23)[C@@H](N1C(=O)CCl)c1ccc(cc1)C(=O)OC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	1S,3R-RSL3,RSL3 1S
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GPX\|\|\|Ferroptosis\|\|\|Glutathione Peroxidase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	440.88
Description	RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of ferroptosis that is selective for tumor cells carrying oncogenic RAS.
Pathways	Apoptosis\|\|\|Metabolism\|\|\|Oxidation-Reduction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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