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Neoline

Neoline

Item no.	TMO-T4S0537-100mg
Manufacturer	TargetMol
CASRN	466-26-2
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.97%
Citations	Suzuki, T., Miyamoto, K., Yokoyama, N., Sugi, M., Kagioka, A., & Kitao, Y. et al. (2016). Processed aconite root and its active ingredient neoline may alleviate oxaliplatin-induced peripheral neuropathic pain.?Journal Of Ethnopharmacology,?186, 44-52. doi: 10.1016/j.jep.2016.03.056
Smiles	[H][C@]12C[C@]3([H])[C@]([H])([C@H]1O)[C@](O)(C[C@@H]2OC)[C@@]1([H])[C@H](OC)[C@@]2([H])C33[C@@H](O)CC[C@@]2(COC)CN(CC)[C@]13[H]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Bullatine B
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Sodium Channel
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	437.57
Description	Neoline is an active ingredient of A. venetum root (PA) that ameliorates oxaliplatin-induced peripheral neuropathy in mice.Neoline inhibits Nav1.7 voltage-gated sodium channel currents (VGSC). It can be used as a labeling compound to determine the quality of PA products used in the study of neuropathic pain.
Pathways	Membrane transporter/Ion channel
Bioactivity	Bullatine B shows analgesic/anti-inflammatory properties.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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