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Atractylenolide I

Atractylenolide I

Item no.	TMO-T5S0167-5mg
Manufacturer	TargetMol
CASRN	73069-13-3
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	97.55%
Citations	Li W, et al. Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro. Exp Cell Res. 2017 Apr 1;353(1):26-34.
Smiles	CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C=C2OC1=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	73069-13-3
Shipping Condition	Cool pack
Available
Manufacturer - Targets	JAK\|\|\|STAT\|\|\|IL Receptor\|\|\|TLR\|\|\|TNF
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	230.3
Description	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88(+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.
Pathways	Angiogenesis\|\|\|Immunology/Inflammation\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors\|\|\|Chromatin/Epigenetic\|\|\|Stem Cells\|\|\|Apoptosis

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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