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Loureirin A

Loureirin A

Item no.	TMO-T5S0896-25mg
Manufacturer	TargetMol
CASRN	119425-89-7
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	0,9984
Smiles	COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	119425-89-7
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Akt\|\|\|PI3K
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	286.32
Description	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related peptide (CRP), ADP and thrombin. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4, inhibiting the synthesis and secretion of α- SMA, TGF- β1and the proliferation of HSCs.
Pathways	Cytoskeletal Signaling\|\|\|PI3K/Akt/mTOR signaling

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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