« Back
Home /
AS2863619

AS2863619

Item no.	TMO-T8378-10mM
Manufacturer	TargetMol
CASRN	2241300-51-4
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Format	Powder
Specific against	other
Purity	1
Smiles	Cl.Cl.Cc1nc2ccc(cc2[nH]1)-n1c(nc2cnccc12)-c1nonc1N
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	2241300-51-4
Shipping Condition	Cool pack
Available
Manufacturer - Targets	STAT\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	405.24
Description	AS2863619 is an oral inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19. Inhibition of CDK8/19 can enhance the activation of STAT5, thereby activating the Foxp3 gene. It can convert antigen-specific effector/memory T cells into Foxp3+ regulatory T cells to study various immune diseases.
Pathways	JAK/STAT signaling\|\|\|Stem Cells\|\|\|Cell Cycle/Checkpoint

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T8378-10mM-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mL x 10 mM (in DMSO)

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question