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PROTAC BRAF-V600E degrader-1

PROTAC BRAF-V600E degrader-1

Item no.	TMO-T8745-10mg
Manufacturer	TargetMol
CASRN	2417296-84-3
Amount	10 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.43%
Citations	Han X R , Chen L , Wei Y , et al. Discovery of Selective Small Molecule Degraders of BRAF-V600E[J]. Journal of Medicinal Chemistry, 2020, XXXX(XXX).
Smiles	FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(C(CCOCCOCCOCCNC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Compound 23
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Raf\|\|\|PROTACs
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	1001.07
Description	PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.
Pathways	MAPK\|\|\|PROTAC

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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