HBT1

Item no.	TMO-T8779-1mg
Manufacturer	TargetMol
CASRN	489408-02-8
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.48%
Citations	Kunugi A , Tajima Y , Kuno H , et al. HBT1, a novel AMPA receptor potentiator with lower agonistic effect, avoided bell-shaped response in in vitro BDNF production[J]. Journal of Pharmacology & Experimental Therapeutics, 2018:jpet.117.245050.
Smiles	Cc1cc(nn1CC(=O)Nc1sc2CCCCc2c1C(N)=O)C(F)(F)F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	489408-02-8,GluR
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GluR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	386.39
Description	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
Pathways	Neuroscience
Bioactivity	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.

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